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The tibial transverse transport corticotomy offers hope as an effective treatment modality for cases of severe diabetic foot ulcer, complicated by clti, to improve wound healing and limb salvage in the lower extremity. Ttt surgery can effectively regenerate the microvascular network in the lower limbs of these patients to promote ulcer healing and increase the chance of limb salvage. The mechanism may be associated with the neovascularization in the ulcerated foot induced by ttt and consequently increased perfusion.
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Throughout the treatment period, we implemented aggressive local wound care coupled with negative pressure wound therapy (125 mmhg, intermittent mode with 5 minutes on and 2 minutes off). Establishing animal model and mechanism for how tibial cortex transverse transport facilitates healing and limb salvage in patients with recalcitrant dfus. All 136 patients underwent tibial cortex transverse distraction (partial corticotomy of the upper tibia, which was in normal condition, followed by 4 weeks of transverse distraction medially then laterally).
In the present study, we confirmed that ttt surgery promoted wound healing via its regulating effects on angiogenesis and immunomodulation, providing more biological mechanisms for its clinical applications in the management of chronic ischaemic diseases.
The tibial transverse transport corticotomy technique is a novel approach and a promising intervention for severe diabetic foot ulcers (dfu) Three cases illustrate successful outcomes with the described procedure in which healing was challenged through conventional treatment methods. Management of severe diabetic foot ulcers (dfus) remains challenging Tibial cortex transverse transport (ttt) facilitates healing and limb salvage in patients with recalcitrant dfus
However, the underlying mechanism is largely unknown,.
